Pessaries List
| SN | Product Name | Type | Indication/Therapeutic Class | BCS Class |
|---|---|---|---|---|
| 1 | Clotrimazole USP 100mg pessaries | Pessaries | Proton Pump Inhibitor (PPI) | Class 2 |
Frequently Asked Questions
Pessaries are solid medicated dosage forms designed for intravaginal administration. They are inserted into the vagina where they melt or dissolve at body temperature to release the active ingredient locally. Pessaries are commonly used to treat vaginal infections such as candidiasis (yeast infections), bacterial vaginosis, and trichomoniasis, as well as for hormone replacement therapy and contraception.
Pharmgenity Health manufactures Clotrimazole USP 100mg pessaries, an antifungal medication used for the treatment of vaginal candidiasis (yeast infections). Clotrimazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby eliminating the infection. We also offer customized pessary formulations for various therapeutic indications.
Both pessaries and suppositories are solid dosage forms that melt at body temperature, but they differ in their site of administration. Pessaries are specifically designed for vaginal administration, typically using a base like PEG or glycerinated gelatin that is compatible with vaginal pH. Suppositories are primarily designed for rectal administration and often use a different base composition such as cocoa butter or hydrogenated vegetable oils.
Pessaries are manufactured using various bases including polyethylene glycol (PEG), glycerinated gelatin, and semi-synthetic glycerides. The choice of base affects the melting point, drug release rate, and stability of the pessary. Bases are selected to ensure the pessary remains solid at room temperature but melts or dissolves at body temperature (37°C) to release the active ingredient effectively at the vaginal site.
Pessaries are typically packaged in PVC/aluminum blister packs or strip packaging to protect them from moisture, heat, and physical damage. They should be stored in a cool, dry place below 25°C to maintain their physical integrity. Each pessary is individually sealed to ensure product stability and hygiene. We provide custom packaging solutions with complete regulatory documentation for global export.